In this episode, Dr. Gladden sits down with Dr. Elizabeth Yurth, an orthopedic surgeon turned longevity physician who has been working with peptides for more than a decade and has spent 20 years at the forefront of longevity medicine. Together, they explore how peptides are not foreign substances, but naturally occurring compounds the body has produced throughout our lives and how their decline with age may play an important role in the aging and regenerative process.
Dr. Yurth explains why peptides may not work as expected when the nervous system is stuck in sympathetic overdrive, why supporting dysfunctional mitochondria requires more than simply “turning them up,” and the three mitochondrial peptides she considers foundational for energy, cellular repair, and longevity. They also explore the eight pillars of regeneration, the importance of screening for malignant cells before using growth-promoting peptides, and why the sequencing and timing of peptide therapies may be just as important as the peptides themselves.
Dr. Yurth also addresses the growing “gym bro” peptide culture, the risks of using peptides without understanding their mechanisms, and why she views peptide replacement through a similar lens as hormone replacement. Whether you are already using peptides, considering starting them, or simply want to better understand how peptide therapies fit into a comprehensive approach to longevity, this episode offers a deeper look at how and why they should be used thoughtfully.
🤓 What you’ll learn:
➡️ How peptides naturally occur in the body and why their production and signaling can change with age
➡️ Why nervous system regulation and mitochondrial health are foundational to successful peptide therapy
➡️ The three mitochondrial peptides Dr. Yurth considers essential for energy, repair, and longevity
➡️ The eight pillars of regeneration and how they work together
➡️ Why peptide sequencing, timing, and individualized protocols matter
➡️ The importance of screening for malignant cells before using growth-promoting peptides
➡️ How to approach peptides safely and strategically rather than following trends or “gym bro” protocols
This episode is for you if:
– You’re curious about peptides and want to understand how they actually work in the body– You’re curious about peptides, GLP-1 medications, and longevity therapies but unsure what’s legit vs. hype
– You’ve tried peptides but haven’t experienced the results you expected and want to understand what may be missing
– You’re interested in longevity, mitochondrial health, regeneration, and a more strategic approach to peptide therapy
In this episode of Gladdon Longevity Podcast, Dr. Yurth and Dr. Gladdon discuss:
✅ Peptides, aging & replacement: Why naturally occurring peptides may decline with age and how peptide therapy can be viewed as part of a broader strategy for healthy aging.
✅ Mitochondria & regeneration: Why mitochondrial health and nervous system regulation need to be addressed before simply trying to “rev up” cellular energy.
✅ The strategy behind peptide therapy: Why the right peptide, in the right sequence and at the right time, may matter more than simply taking more peptides.
🎧 Click below to tune in to Gladden Longevity Podcast – The Peptide Protocol That Changes Everything About Recovery… | Ep. 333
Interested in learning more about how you can improve your health & longevity with cellular medicine? Get started here with Boulder Longevity Institute.
