BLI’s Packages are meant for those looking to target or address a specific health goal or concern. Packages include clinician-selected formulations known for their synergistic impacts and well-documented research on key health priorities.
Packages are a one-time cost and include:
- ~3 months (10-12 week) supply of Compounded Medications (based on dosing)
- Injection Supplies (i.e. Syringes if applicable)
- One 30 Minute Package Check-In Appointment with a BLI Specialist
Packages DO NOT include:
- Initial Package Consult Appointment (required for first-time BLI clients) – $250
- Shipping costs
- Non Package Related Follow-Up Appointments (i.e. Imaging Reviews, Lab Reviews, Appts to discuss different/new questions not related to your original Package)
Sirolimus Package
$375
Evolving as one of the most well-researched anti-aging drugs, rapamycin, also known as sirolimus, has shown promise as a powerful longevity drug known to extend lifespan by up to 20% in most species.
Components
Aesthetic Package – Hair
$450
One of the common fears of aging is the receding hairline and hair thinning. Did you know that chronic stress can also lead to increased hair loss? Certain peptides are well-known for their rejuvenation effects, especially when it comes to hair regrowth and hair health. By stimulating the follicle at its root, this synergistic combination of ingredients can help you regrow and maintain a healthy head of hair.
Components
- GHK-Cu Scalp Foam with Melatonin, Tretinoin & Caffeine
- Does not include appointment
BCAA Package
$480
Branched-chain amino acids (BCAAs) are best known for their influence on improved muscle growth and exercise performance. They may also help with weight loss and reducing fatigue after exercise. Amino acids are the building blocks of protein in our body. Commonly found in supplement capsules or powder form, BCAAs are made up of the three essential amino acids – leucine, isoleucine, and valine. To increase uptake and get even further benefits, the BCAA Package includes a comprehensive combination of glutamine, arginine, carnitine, leucine and isoluecine (GACLIV) easily absorbed through a simple subcutaneous injection.
Pentosan (PPS) Package
$749
PPS is a beneficial regenerative medication that works to address the entire inflammatory process in ways that typical treatments for orthopedic pain – anti-inflammatories, steroids, joint replacements – do not. Pentosan works through various mechanisms like pain control, halting the progression of degeneration, and encouraging an environment for regeneration.
Components
Weight Management Package
Semaglutide – $995
Tirzepatide – $1,665
This package is for those looking to target weight loss through the use of advanced, cellular-medicine-based weight loss therapies. Using the GLP-1 agonist, Semaglutide or the dual GIP and GLP-1 receptor agonist Tirzepatide, the Weight Management Package works to effectively enhance the uptake and disposal of glucose efficiently to improve fat loss and energy production resulting in sustained weight loss. (Ginger/Pyridoxine HCL Capsules available as add-on to help with nausea if needed.)
Aesthetic Package – Skin
$720
Offered in a readily-absorbed serum form, this combination of peptides helps to enhance skin elasticity and integrity. The synergy between these compounds work internally and externally to increase peptides focused on skin smoothing, natural collagen production, and decreased DNA damage and inflammation.
Components
- GHK-Cu Facial Serum with Argireline & Leuphasyl
- Does not include appointment
Immune Package
$1,665
The Immune Package looks at boosting your immune system by giving your body the tools it needs to strengthen your body’s natural immune modulators at the cellular level. The well-researched peptide, Thymosin Alpha-1 or TA1, is naturally occurring in the thymus and has long been recognized for modifying, enhancing, and restoring immune function.
Components
Foundational Gut Health Package
$1,950
BPC and KPV are two leaders when it comes to peptides for enhancing overall gut health. Both compounds are well documented in their ability to decrease inflammation and proinflammatory cytokine levels. They have been used in treatment of a multitude of gastrointestinal (GI) issues, including colitis, Crohn’s, Irritable Bowel Disease, and other digestive disorders.
Components
Foundational Healing Package
$2,370
Designed to combine the science of cellular medicine with the opportunity of regenerative orthopedics, the Basic Healing Package includes compounds well-researched for the healing capabilities.
Components
Advanced Gut Health Package
$2,950
Bringing the benefits of BPC and KPV outlined in the Foundational Gut Health Package, the Advanced Gut Health Package includes Larazotide as an added powerhouse compound for healing the gut. Larazotide is a synthetic peptide designed to tighten the adhesions between tight junction cells lining the small intestine in order to restore the intestine to its normal state.
Components
Advanced Hair Growth Package
$2,995
For those looking to target hair loss beyond the use of topical creams, this package offers a combination of immune-modulating and regrowth peptides aimed at managing, stopping and reversing hair loss at the systemic level.
Advanced Healing Package
$3,695
For those looking for targeted healing support beyond the Basic Healing Package, the Premium Healing Package takes the peptide power of BPC-157 and TB4 combined with further researched-back therapies for optimized healing.
ARA-290 Package
$4,650
ARA-290 works by activating the innate repair receptor to induce anti-inflammatory and tissue repair mechanisms. ARA-290 is used to treat neuropathic pain, reducing nerve pain while helping repair damaged nerves, decreases systemic inflammation, and accelerates wound healing. ARA has also been shown to help regulate blood sugar levels.
Components
Longevity Package
$5,550
For those looking for the powerhouse combination of longevity peptides, the Longevity Package brings together the most well-vetted cellular renewal and anti-aging compounds to help heal, restore, and strengthen your bodies key pathways.
BPC-157
Pentadecapeptide BPC-157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) and is well known for its healing, as well as gut health management abilities. Experimentally BPC has been demonstrated to accelerate the healing of many different wounds, including tendon-to-bone healing and superior healing of damaged ligaments.
The use of BPC-157 is thought to speed up the growth and spread of fibroblasts and to increase rates of oxidative resistance. Fibroblasts are a specialized type of cell found in connective tissues. These cells are involved in the creation of collagen. In addition to its effects on fibroblast production. BPC also affects F-actin formation (which is involved in the spreading of fibroblasts).
Additionally, BPC has been successfully used to increase the rate of collagen reformation following surgery and has become a well-researched fracture and wound healing agent due to its association with improved bone health.
Thymosin Beta-4 (TB4)
Thymosin Beta-4 (Tβ4) is a hormone secreted by the thymus gland. Not to be confused with the thyroid gland, the thymus produces a hormone called Thymosin.
Thymosin stimulates T cell (T lymphocyte) production. Thymosin also educates these cells on what to attack and, importantly, what not to attack (ourselves – a phenomenon known as autoimmunity.)
After gaining their production and education from thymosin, the T lymphocytes move off to do battle against threats like viruses and infections. The activity of the thymus during this young age leads to a notable rarity of autoimmune disorders amongst younger patients.
As we exit puberty, the gland becomes less active and shrinks away. As the thymus does less and less, our immune system is left with its dwindling previous education and, for many, can become dysfunctional with age. The dysfunction can lead to failed attacks on viruses or infections and can bring about autoimmune disorders. The reduction of thymosin is a critical part of aging.
Tβ4 is the predominant form of thymosin. Thus, the introduction of Tβ4 is valuable in supporting the immune system and its continued optimal function.
The Tβ4 peptide has numerous uses outside of immune support. It is an effective tool to fight inflammation and help with tissue repair post-injury.
GHK-Cu (Injectable)
GHK-Cu is a tripeptide found in our very own plasma. It is a copper complex, making it very important to overall health and wellness. While it is widely known for its cosmetic uses, including as a Botox alternative, GHK-Cu research is revealing the value of this tripeptide to other areas of our health.
Research indicates that GHK-Cu has the ability to reset the genes of diseased cells in patients with cancer or COPD to a state of health. This gene expression reset may hold significant value for battling the primary offender of aging – the loss of the ability to repair DNA.
GHK-Cu has also shown positive impacts as an anti-inflammatory. As chronic inflammation leads to disease, finding effective anti-inflammatory therapies is imperative to improving healthspan.
This same anti-inflammatory property combined with the potential for repairing DNA seem to be involved in the influence of GHK-Cu on gut health.
The beneficial properties of GHK-Cu are vast. Nerve growth, blood vessel generation, wound healing, and anti-inflammatory properties all highlight how GHK-Cu is an invaluable peptide. Injecting this tripeptide offers the opportunity for the body to take full advantage of the benefits of GHK-Cu.
Unfortunately, GHK-Cu is plentiful in our plasma until it begins to decline in volume. By age 60, it is estimated we will have lost about 60% of our GHK-Cu. The ability to add GHK-Cu to our bodies by injection could hold a key to significant anti-aging benefits.
References:
GHK-Cu (Topical)
GHK-Cu is a tripeptide found in our very own plasma. It is a copper complex, making it very important to overall health and wellness.
Topical applications of GHK-Cu utilize the same properties introduced by the injectable variation of this peptide. Anti-inflammatory and regenerative properties combine for both cosmetic and therapeutic benefits.
The peptide combined with a serum or cream can smooth skin, reduce or eliminate wrinkles, and tighten areas of skin that have begun to weaken or loosen.
Additionally, some research is indicating that topical applications of GHK-Cu could be useful for the reduction of stress, anxiety, and may even increase pain tolerance.
While topical applications can be effective for certain applications, the injectable may be more beneficial for uses outside of dermatological or cosmetic purposes.
Nandrolone
This anabolic steroid is often scoffed at because of its association with extreme bodybuilding. However, nandrolone decanoate has many benefits to overall health and healthspan.
In addition to its obvious ability to aid in increasing muscle mass, it can help regulate cortisol. Too much cortisol can delay recovery from injury or post-exercise soreness.
Nandrolone decanoate also aids in collagen production and can improve bone density. Most of our tissue is made from collagen, making collagen synthesis vital to ligament and tendon health.
An increase in testosterone can also be encouraged by nandrolone decanoate. Testosterone levels decline as we age, leading to a loss in lean muscle mass and an increase in fatigue and weight. Optimizing hormones like testosterone is essential to maintaining health as we age.
Semaglutide
Semaglutide has received an increase in press coverage of late, due to its recent approval in the United States as a weight loss and weight management medication. Semaglutide is a glucagon-like peptide-1 receptor (GLP-1) agonist that increases insulin, thereby lowering blood sugar levels. It has been noted to enhance beta cell growth in the pancreas, also potentially helping with insulin production. It inhibits glucagon, the hormone that increases blood sugar, and can reduce food intake via appetite reduction.
Stimulating GLP-1 can improve function in most organs. This can provide benefits to combat aging diseases by improving cardiac output, reducing inflammation, helping with kidney function, adding neural protection and regeneration, and increasing glucose to muscles.
It is important to start with a low dose and work up from there. Heart rate increases can occur but the cardioprotective qualities of the drug generally outweigh that risk. Those with a family history of rare medullary thyroid cancer would be advised against taking semaglutide.
Overall, semaglutide in its various forms is a safe medication with tremendous health benefits. Discoveries like the neuroprotective benefits of semaglutide are exciting, as the current arsenal of ways to impact those with dementia or other aging diseases is limited.
Ginger/Pyridoxine HCL (B6) Capsules
One common side-effect of Semaglutide is nausea, especially when first beginning a dosing protocol. To help alleviate this, Ginger/Pyridoxine HCL (B6) capsules are included in the package.
Thymosin Alpha-1 (TA1)
Thymosin Alpha-1 is a peptide naturally occurring in the thymus that has long been recognized for modifying, enhancing, and restoring immune function. TA1 has been utilized in the treatment of immunocompromised states and malignancies, as an enhancer of vaccine response, and as a means of curbing morbidity and mortality in sepsis and numerous infections. Studies have postulated that TA1 could help improve the outcome in severely ill coronavirus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how TA1 could prevent the excessive activation of T cells.
References:
Pentosan Polysulfate (PPS)
PPS is a sulfated polysaccharide (a complex sugar molecule with an attached sulfate group) derived from beechwood. Traditionally used to treat inflammatory bladder pain, recent research highlights PPS to target degenerative joint issues.
Clinical and pre-clinical models indicate PPS as useful for:
- Managing osteoarthritic pain
- Cartilage restoration
- Recovery of bony edema (bone bruises)
- Nourishing articular cartilage surfaces
- Preventing cartilage degradation
Avoid use and/or use caution in patients with an allergy to any components of PPS, Anti-coagulant therapy (heparin, coumadin, etc.), Personal and/or strong family history of pigmentary macular degeneration, Anyone advised to d/c blood thinners
GACLIV
This collection of amino acids includes glutamine, arginine, carnitine, leucine, isoleucine, and valine. This formula replaces vital amino acids lost due to stress, illness, or insufficient diet.
Even for those without a significant deficiency, supplementing essential amino acids can improve healthspan and increase longevity.
Glutamine
Glutamine provides energy to all cells. It can promote lean muscle mass development, endurance, and recovery after exercise. Glutamine is quickly used up during stressful moments, making supplementation beneficial.
Arginine
Arginine has significant anti-inflammatory properties, including relaxing blood vessels and improving circulation. This encourages a healthy cardiovascular system, improving cardiac health.
It also acts as a precursor for creatine, a vital element to supplying muscle with energy for exercise and performance.
There is some evidence showing arginine encourages the production of human growth hormone (HGH), a vital hormone in the quest for healthy aging. Tissue repair, skin health, and lean muscle mass are all impacted by the availability of HGH.
Carnitine
Carnitine is also a source of energy. This amino acid is valuable for encouraging fat burning, improving endurance, and reducing soreness after exercise.
Leucine
Leucine is not created by our bodies but is found in high-protein foods. Supplementing leucine ensures it is readily available.
This branched-chain amino acid has been shown to positively impact glucose uptake and insulin sensitivity, making it a valuable tool in the effort to control blood sugar levels. Leucine is also vital to muscle growth, skin quality, wound repair, and bone health.
Isoleucine
The second of three branched-chain amino acids, isoleucine is known for its ability to encourage glucose uptake and use during exercise. Studies indicate that isoleucine may be the most effective branched chain amino acid at ensuring the proper use of glucose – both in uptake and breakdown.
Valine
The final branched-chain amino acid impacts focus, coordination, and emotional balance. Valine positively impacts muscle growth, tissue repair, and energy levels.
References:
CJC/Ipamorelin
Growth hormone secretagogues like CJC and Ipamorelin work in a homeostatic way, telling your body to release growth hormone (GH). We generally think about hormonal decline but often forget about the marked drop in growth hormone starting around age 20.
Encouraging a steady, predictable supply of human growth hormone (HGH) under the supervision of a certified peptide expert can improve myriad aspects of health and longevity.
MOTS-c
MOTS-c is a mitochondrial peptide produced by the world-famous mitochondria. While its release has various signaling functions inside the cell, it also impacts other biological processes in the body.
This peptide has been shown to have impacts on obesity, diabetes, exercise performance, and health in general via its ability to enhance glucose metabolism.
References:
Epitalon
This peptide is the synthetic form of Epithalamin, which is produced by the pineal gland. The peptide is used by the body to encourage telomerase production, which is vital to the process that protects DNA by helping cells reproduce telomeres.
DNA protection is essential to DNA replication, making the production of telomerase essential to health and longevity. As we age, telomerase production drops naturally. Introducing it as a supplement has a positive impact on longevity.
Additionally, studies indicate that Epitalon helps with circadian rhythm and cortisol control (the hormone associated with stress.)
References:
Larazotide
Larazotide acetate (LA) is a synthetic peptide designed to tighten the adhesions between tight junction cells lining the small intestine in order to restore the intestine to its normal state. It is being studied in people with celiac disease as an adjunct therapeutic agent to enhance the function of the intestinal barrier. Larazotide is an antagonist to Zonulin, which loosens tight junctions and allows for highly inflammatory viral particles to get into circulation. Larazotide prevents breakdown of tight junctions, limiting antigen trafficking.
References:
PEG-MGF
MGF, also known as IGF-1Ec, is a variant of the systemic IGF-1 produced by the liver. Unlike systemic IGF-1, MGF is expressed specifically in response to muscle damage and is involved in repairing and adapting the muscle. It is expressed as a pulse after muscle damage and helps activate muscle stem cells to repair the muscle and contribute to growth. MGF and IGF-1 have similar functions in repairing and growing new cells. In order to have a longer effect, MGF must be PEGylated as its natural half-life is only minutes. Studies have shown that there is a differential expression of IGF-1 isoforms in response to exercise-induced muscle damage, with a rapid increase in MGF expression followed by a prolonged increase in IGF-1Ea and IGF-1Eb. Research has also shown that the action of synthetic MGF differs from that of mature IGF-1 and has its own unique effects on muscle cells. These findings suggest that MGF and IGF-1 may act as separate agents in muscle regeneration.
References:
- Philippou, Anastassios & Papageorgiou, E & Bogdanis, Gregory & Halapas, Antonios & Sourla, A & Maridaki, Maria & Pissimissis, Nikolas & Koutsilieris, Michael. (2009). Expression of IGF-1 Isoforms after Exercise-induced Muscle Damage in Humans: Characterization of the MGF E Peptide Actions In Vitro. In vivo (Athens, Greece). 23. 567-75.
BPC/KPV
KPV is an anti-inflammatory peptide that has the potential to reduce inflammation in intestinal diseases such as Crohn’s and Ulcerative Colitis. By blocking the production and release of proinflammatory cytokines, KPV helps to curb the immune response that leads to inflammation. In studies, KPV has demonstrated efficacy in reducing inflammation and promoting the healing of the gut lining in patients with Inflammatory Bowel Diseases and ulcers. For example, in a study with mice with Ulcerative Colitis, KPV was found to lead to significant improvements in body weight, colon length, and symptoms. When combined with BPC, KPV has shown to be an even more potent anti-inflammatory agent.
Sirolimus (Rapamycin)
It is widely used in the longevity field as a senolytic, with low-dose administration once a week to remove old, damaged cells and promote the growth of healthy ones. High doses of Rapamycin have been used as a chemotherapy agent and immunosuppressant for transplant patients, but at low doses it acts as a rejuvenating agent. For more information on its effects and benefits, see the review article linked here:
Tirzepatide
Tirzepatide not only helps regulate blood sugar levels in people with type 2 diabetes, but it may also have potential weight loss and anti-aging effects. In clinical trials, some patients experienced weight loss while taking the medication, although more research is needed to fully understand this effect. Tirzepatide may also have anti-aging properties due to its effects on glucose and insulin regulation, as well as its potential impact on oxidative stress and inflammation. However, these potential benefits are still being studied and more research is needed to determine their full extent and implications.
ARA-290
ARA-290 (cibinetide) is a peptide that was made from erythropoietin and is currently in phase 2 trials within the US. ARA-290 works by activating the innate repair receptor to induce anti-inflammatory and tissue repair mechanisms. ARA-290 is used to treat neuropathic pain in patients with diabetic neuropathy, small fiber neuropathy, rheumatoid arthritis, sarcoidosis, covid induced neuropathy, and research into others is on-going and extremely promising. ARA-290 reduces nerve pain & helps repair damaged nerves, decreases systemic inflammation, accelerates wound healing, and even has been shown to help regulate blood sugar levels.
ARA-290 is prescribed for a 3 month period. The patient is started on the “high dose” for the first 6 weeks and then lowered to the “low dose” for the next 6 weeks. ARA-290 has an incredibly high safety profile, and as of yet, no study has demonstrated any side effects or toxicity; however some patients have reported an elevated BP, elevated heart rate, elevated liver enzymes, or nausea/vomiting, but these were not confirmed to be due to the medication, and could be coincidental/not drug related. Because ARA-290 is an injectable medication and not a pill, the actual injection may lead to injection site irritation or bruising, or an infection; but overall patients report it is tolerated extremely well, and results are seen in some patients as quickly as 2-3 weeks.
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