BLI Packages

BPC-157

Pentadecapeptide BPC-157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) and is well known for its healing, as well as gut health management abilities. Experimentally BPC has been demonstrated to accelerate the healing of many different wounds, including tendon-to-bone healing and superior healing of damaged ligaments.

The use of BPC-157 is thought to speed up the growth and spread of fibroblasts and to increase rates of oxidative resistance. Fibroblasts are a specialized type of cell found in connective tissues. These cells are involved in the creation of collagen. In addition to its effects on fibroblast production. BPC also affects F-actin formation (which is involved in the spreading of fibroblasts).

Additionally, BPC has been successfully used to increase the rate of collagen reformation following surgery and has become a well-researched fracture and wound healing agent due to its association with improved bone health.

Thymosin Beta-4 (TB4)

Thymosin Beta-4 (Tβ4) is a hormone secreted by the thymus gland. Not to be confused with the thyroid gland, the thymus produces a hormone called Thymosin.

Thymosin stimulates T cell (T lymphocyte) production. Thymosin also educates these cells on what to attack and, importantly, what not to attack (ourselves – a phenomenon known as autoimmunity.)

After gaining their production and education from thymosin, the T lymphocytes move off to do battle against threats like viruses and infections. The activity of the thymus during this young age leads to a notable rarity of autoimmune disorders amongst younger patients.

As we exit puberty, the gland becomes less active and shrinks away. As the thymus does less and less, our immune system is left with its dwindling previous education and, for many, can become dysfunctional with age. The dysfunction can lead to failed attacks on viruses or infections and can bring about autoimmune disorders. The reduction of thymosin is a critical part of aging.

Tβ4 is the predominant form of thymosin. Thus, the introduction of Tβ4 is valuable in supporting the immune system and its continued optimal function.

The Tβ4 peptide has numerous uses outside of immune support. It is an effective tool to fight inflammation and help with tissue repair post-injury.

GHK-Cu (Injectable)

GHK-Cu is a tripeptide found in our very own plasma. It is a copper complex, making it very important to overall health and wellness. While it is widely known for its cosmetic uses, including as a Botox alternative, GHK-Cu research is revealing the value of this tripeptide to other areas of our health.

Research indicates that GHK-Cu has the ability to reset the genes of diseased cells in patients with cancer or COPD to a state of health. This gene expression reset may hold significant value for battling the primary offender of aging – the loss of the ability to repair DNA.

GHK-Cu has also shown positive impacts as an anti-inflammatory. As chronic inflammation leads to disease, finding effective anti-inflammatory therapies is imperative to improving healthspan.

This same anti-inflammatory property combined with the potential for repairing DNA seem to be involved in the influence of GHK-Cu on gut health.

The beneficial properties of GHK-Cu are vast. Nerve growth, blood vessel generation, wound healing, and anti-inflammatory properties all highlight how GHK-Cu is an invaluable peptide. Injecting this tripeptide offers the opportunity for the body to take full advantage of the benefits of GHK-Cu.

Unfortunately, GHK-Cu is plentiful in our plasma until it begins to decline in volume. By age 60, it is estimated we will have lost about 60% of our GHK-Cu. The ability to add GHK-Cu to our bodies by injection could hold a key to significant anti-aging benefits.

References:

• ncbi.nlm.nih.gov

GHK-Cu (Topical)

GHK-Cu is a tripeptide found in our very own plasma. It is a copper complex, making it very important to overall health and wellness.

Topical applications of GHK-Cu utilize the same properties introduced by the injectable variation of this peptide. Anti-inflammatory and regenerative properties combine for both cosmetic and therapeutic benefits.

The peptide combined with a serum or cream can smooth skin, reduce or eliminate wrinkles, and tighten areas of skin that have begun to weaken or loosen.

Additionally, some research is indicating that topical applications of GHK-Cu could be useful for the reduction of stress, anxiety, and may even increase pain tolerance.

While topical applications can be effective for certain applications, the injectable may be more beneficial for uses outside of dermatological or cosmetic purposes.

Nandrolone

This anabolic steroid is often scoffed at because of its association with extreme bodybuilding. However, nandrolone decanoate has many benefits to overall health and healthspan.

In addition to its obvious ability to aid in increasing muscle mass, it can help regulate cortisol. Too much cortisol can delay recovery from injury or post-exercise soreness.

Nandrolone decanoate also aids in collagen production and can improve bone density. Most of our tissue is made from collagen, making collagen synthesis vital to ligament and tendon health.

An increase in testosterone can also be encouraged by nandrolone decanoate. Testosterone levels decline as we age, leading to a loss in lean muscle mass and an increase in fatigue and weight. Optimizing hormones like testosterone is essential to maintaining health as we age.

Semaglutide

Semaglutide has received an increase in press coverage of late, due to its recent approval in the United States as a weight loss and weight management medication. Semaglutide is a glucagon-like peptide-1 receptor (GLP-1) agonist that increases insulin, thereby lowering blood sugar levels. It has been noted to enhance beta cell growth in the pancreas, also potentially helping with insulin production. It inhibits glucagon, the hormone that increases blood sugar, and can reduce food intake via appetite reduction.

Stimulating GLP-1 can improve function in most organs. This can provide benefits to combat aging diseases by improving cardiac output, reducing inflammation, helping with kidney function, adding neural protection and regeneration, and increasing glucose to muscles.

It is important to start with a low dose and work up from there. Heart rate increases can occur but the cardioprotective qualities of the drug generally outweigh that risk. Those with a family history of rare medullary thyroid cancer would be advised against taking semaglutide.

Overall, semaglutide in its various forms is a safe medication with tremendous health benefits. Discoveries like the neuroprotective benefits of semaglutide are exciting, as the current arsenal of ways to impact those with dementia or other aging diseases is limited.

Ginger/Pyridoxine HCL (B6) Capsules

One common side-effect of Semaglutide is nausea, especially when first beginning a dosing protocol. To help alleviate this, Ginger/Pyridoxine HCL (B6) capsules are included in the package.

Thymosin Alpha-1 (TA1)

Thymosin Alpha-1 is a peptide naturally occurring in the thymus that has long been recognized for modifying, enhancing, and restoring immune function. TA1 has been utilized in the treatment of immunocompromised states and malignancies, as an enhancer of vaccine response, and as a means of curbing morbidity and mortality in sepsis and numerous infections. Studies have postulated that TA1 could help improve the outcome in severely ill coronavirus disease 2019 patients by repairing damage caused by overactivation of lymphocytic immunity and how TA1 could prevent the excessive activation of T cells.

References:

• ncbi.nlm.nih.gov

Pentosan Polysulfate (PPS)

PPS is a sulfated polysaccharide (a complex sugar molecule with an attached sulfate group) derived from beechwood. Traditionally used to treat inflammatory bladder pain, recent research highlights PPS to target degenerative joint issues.

Clinical and pre-clinical models indicate PPS as useful for:

• Managing osteoarthritic pain
• Cartilage restoration
• Recovery of bony edema (bone bruises)
• Nourishing articular cartilage surfaces
• Preventing cartilage degradation

Avoid use and/or use caution in patients with an allergy to any components of PPS, Anti-coagulant therapy (heparin, coumadin, etc.), Personal and/or strong family history of pigmentary macular degeneration, Anyone advised to d/c blood thinners

GACLIV

This collection of amino acids includes glutamine, arginine, carnitine, leucine, isoleucine, and valine. This formula replaces vital amino acids lost due to stress, illness, or insufficient diet.

Even for those without a significant deficiency, supplementing essential amino acids can improve healthspan and increase longevity.

Glutamine

Glutamine provides energy to all cells. It can promote lean muscle mass development, endurance, and recovery after exercise. Glutamine is quickly used up during stressful moments, making supplementation beneficial.

Arginine

Arginine has significant anti-inflammatory properties, including relaxing blood vessels and improving circulation. This encourages a healthy cardiovascular system, improving cardiac health.

It also acts as a precursor for creatine, a vital element to supplying muscle with energy for exercise and performance.

There is some evidence showing arginine encourages the production of human growth hormone (HGH), a vital hormone in the quest for healthy aging. Tissue repair, skin health, and lean muscle mass are all impacted by the availability of HGH.

Carnitine

Carnitine is also a source of energy. This amino acid is valuable for encouraging fat burning, improving endurance, and reducing soreness after exercise.

Leucine

Leucine is not created by our bodies but is found in high-protein foods. Supplementing leucine ensures it is readily available.

This branched-chain amino acid has been shown to positively impact glucose uptake and insulin sensitivity, making it a valuable tool in the effort to control blood sugar levels. Leucine is also vital to muscle growth, skin quality, wound repair, and bone health.

Isoleucine

The second of three branched-chain amino acids, isoleucine is known for its ability to encourage glucose uptake and use during exercise. Studies indicate that isoleucine may be the most effective branched chain amino acid at ensuring the proper use of glucose – both in uptake and breakdown.

Valine

The final branched-chain amino acid impacts focus, coordination, and emotional balance. Valine positively impacts muscle growth, tissue repair, and energy levels.

References:

• ncbi.nlm.nih.gov/24806638/
• ncbi.nlm.nih.gov/30843485/

CJC/Ipamorelin

Growth hormone secretagogues like CJC and Ipamorelin work in a homeostatic way, telling your body to release growth hormone (GH). We generally think about hormonal decline but often forget about the marked drop in growth hormone starting around age 20.

Encouraging a steady, predictable supply of human growth hormone (HGH) under the supervision of a certified peptide expert can improve myriad aspects of health and longevity.

MOTS-c

MOTS-c is a mitochondrial peptide produced by the world-famous mitochondria. While its release has various signaling functions inside the cell, it also impacts other biological processes in the body.

This peptide has been shown to have impacts on obesity, diabetes, exercise performance, and health in general via its ability to enhance glucose metabolism.

References:

• ncbi.nlm.nih.gov

Epitalon

This peptide is the synthetic form of Epithalamin, which is produced by the pineal gland. The peptide is used by the body to encourage telomerase production, which is vital to the process that protects DNA by helping cells reproduce telomeres.

DNA protection is essential to DNA replication, making the production of telomerase essential to health and longevity. As we age, telomerase production drops naturally. Introducing it as a supplement has a positive impact on longevity.

Additionally, studies indicate that Epitalon helps with circadian rhythm and cortisol control (the hormone associated with stress.)

References:

• ncbi.nlm.nih.gov

Larazotide

Larazotide acetate (LA) is a synthetic peptide designed to tighten the adhesions between tight junction cells lining the small intestine in order to restore the intestine to its normal state. It is being studied in people with celiac disease as an adjunct therapeutic agent to enhance the function of the intestinal barrier. Larazotide is an antagonist to Zonulin, which loosens tight junctions and allows for highly inflammatory viral particles to get into circulation. Larazotide prevents breakdown of tight junctions, limiting antigen trafficking.

References:

• ncbi.nlm.nih.gov